Rutgers ORA

Office of Research and Economic Development (ORED)

Mass Spectrometer

Department : Environmental and Occupational Health Sciences Institute (EOHSI)

A magnetic sector High Resolution Inductively Coupled Plasma Mass Spectrometer (ICPMS) with significantly higher resolution than quadrapole instruments allows for resolution of isobaric interferences of the analyte atom away from the molecular isobar.  It allows for quantiation of non-easily ionizable elements such as boron in the presence of  matrices with overlapping molecular isobars

Department : Environmental and Occupational Health Sciences Institute

The LC pump can handle the widest array of gradient conditions and mobile phase switching.  It has been dedicated to the analysis of pharmaceutical analytes requiring changes in both gradient and ionization polarity and is a more sensitive instrument than the LCQ.

Department : New Jersey Institute for Food, Nutrition, and Health

The ABSciex 4000QTrap is a hybrid triple quadrupole-linear ion trap mass spectrometer with a variety of available scan modes.  ESI, APCI, and APPI ion sources are available.  We find that the ESI and APPI sources complement each other well; the APPI source better ionizes several lipid classes that are not ionized as well by ESI.  The system is interfaced with a Dionex UltiMate 3000 liquid chromatograph with ternary gradient capabilities, temperature-controlled autosampler, thermostatted column oven, and PDA detector.  

Department : Newark College of Arts and Sciences - Department of Chemistry

The Apex-ultra 70 hybrid fourier transform mass spectrometer (FTMS) - Bruker Daltonics - is equipped with a 7.0 T actively shielded, high-stability magnet, and an Apollo II Dual ESI/MALDI source to provides simultaneous operation in both modes. The ESI source has an ion funnel and a spray chamber with a grounded off-axis sprayer. The MALDI source has computer controlled X-Y stage for scout-385 MTP target plates. Additional instrument capabilities are HPLC and nanospray experiments.

Department : Center for Advanced Biotechnology and Medicine

The ThermoFisher LTQ operated in nano LC mode is routinely used in tandem mass spectrometry experiments to identify peptides present at sub-femtomole levels.   In practice, we can identify proteins in gel bands that are present at the lower levels detectable by silver staining (~1 ng). The instrument is also operated at higher flow rates for other applications such as H-D exchange. This instrument is generally operated by facility staff but some highly experienced users are granted direct access.